By train:
- Railway line Empoli - Siena - Chiusi, get off at the station of Montepulciano.
- Railway line Milan - Rome, get off at the station of Terontola/Cortona (22 km.) or at the station of Chiusi/Chianciano Terme (24 km). 

By car:
- Motorway Milan - Rome A1 (E35): exit at the Valdichiana / Bettolle toll; then take the road on your left towards Torrita di Siena until you reach Abbadia di Montepulciano.
- State Road SS2 "Cassia": exit at the junction near Gallina and take the road to Chianciano, then to Montepulciano and you finally reach Abbadia di Montepulciano.
- State road Siena-Perugia: exit at Pietraia di Cortona, go in direction Montepulciano, to Valiano and you finally reach Abbadia di Montepulciano.